2018阿司匹林、替格瑞洛联合应用在不稳定型心绞痛治疗中的效果探讨

5694617

　　【摘要】 目的 分析阿司匹林、替格瑞洛联合应用在不稳定型心绞痛治疗中的效果。方法 77例不稳定型心绞痛患者， 采用随机数字表法分为对照组（39例）及观察组（38例）。对照组应用阿司匹林+氯吡格雷治疗， 观察组应用阿司匹林+替格瑞洛治疗。比较两组的治疗有效性和安全性。结果 观察组的总有效率为94.74%， 高于对照组的79.49%， 差异具有统计学意义（χ2=3.961， P=0.0470.05）。随访6个月， 观察组的心血管事件发生率为5.26%， 低于对照组的23.08%， 差异具有统计学意义（χ2=4.988， P=0.026 http://
　　【关键词】 阿司匹林；替格瑞洛；不稳定型心绞痛
　　DOI：10.14163/j.cnki.11-5547/r.2017.36.060
　　Discussion on effect of aspirin combined with ticagrelor in the treatment of unstable angina pectoris XING Ran. Beijing Changping District Hospital， Beijing 102200， China
　　【Abstract】 Objective To analyze the effect of aspirin combined with ticagrelor in the treatment of unstable angina pectoris. Methods A total of 77 patients with unstable angina pectoris were divided by random number table method into control group （39 cases） and observation group （38 cases）. The control group was treated with aspirin + clopidogrel， and the observation group was treated with aspirin + ticagrelor. Comparison were made on treatment effectiveness and safety in two groups. Results The observation group had higher total effective rate as 94.74% than 79.49% in the control group， and the difference was statistically significant （χ2=3.961， P=0.0470.05）. After 6 months of folllow-up， the observation group had lower incidence of cardiovascular events as 5.26% than 23.08% in the control group， and the difference was statistically significant （χ2=4.988， P=0.0260.05）， 具有可比性。