[摘要] 目的 探讨腺苷蛋氨酸中剂量对治疗病毒性肝炎的疗效。方法 方便选择该院在2014年2月―2016年2月期间收治的病毒性肝炎患者85例,以随机综合序贯法将患者分为对照组和观察组,两组均予以常规治疗辅以腺苷蛋氨酸治疗,其中观察组(43例)使用2 000 mg/d的大剂量,对照组(42例)使用1 000 mg/d的小剂量,比较两组患者的治疗效果。结果 观察组的治疗有效率为93.0%,高于对照组的76.2%(P http://
[关键词] 腺苷蛋氨酸;病毒性肝炎;剂量;嗜肝病毒
[中图分类号] R512 [文献标识码] A [文章编号] 1674-0742(2017)11(a)-0128-03
[Abstract] Objective To study the curative effect of dose in ademetionine in treatment of virus hepatitis. Methods 85 cases of patients with virus hepatitis admitted and treated in our hospital from February 2014 to February 2016 were convenient selected and randomly divided into two groups, both groups were treated with routine therapy assisted by ademetionine, the observation group with 43 cases used the 2 000 mg/d large dose, while the control group with 42 cases used the 1 000 mg/d small dose, and the treatment effect was compared between the two groups. Results The treatment effective rate in the observation group was higher than that in the control group(93.0% vs 76.2%)(P统计学意义(P>0.05),可进行比较。
1.2 纳入标准
患者有食欲减退、乏力、巩膜黄染、恶心情况,伴有血清ALT的反复升高,经病原学或血清学检查确诊,均符合中华医学会传染病与寄生虫病学分会、肝病学分会制定的《病毒性肝炎防治方案》中对病毒性肝炎的诊断标准[4]。
1.3 排除标准
①排除慢性血吸虫病、华支睾吸虫病肝癌,胆管癌、胰头癌、暴发性脂肪肝、肝硬化等肝脏外其他阻塞疾病;②排除凝血酶原活动度