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2018脑梗死患者同型半胱氨酸、游离脂肪酸和超氧化物歧化酶的水平研究

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发表于 2018-8-15 21:26:26 | 显示全部楼层 |阅读模式
  【摘要】 目的:探讨脑梗死与血清同型半胱氨酸(HCY)、游离脂肪酸(NEFA)和超氧化物歧化酶 (SOD) 水平予脑梗死的关系。方法:选取69例脑梗死患者作为研究对象,选取同期健康体检者62例作为对照组,运用东芝2000FR全自动生化分析仪测定血清同型半胱氨酸(HCY)、游离脂肪酸(NEFA)、超氧化物歧化酶(SOD)水平。结果:脑梗死组血清同型半胱氨酸和游离脂肪酸水平均高于对照组,差异均有统计学意义(t=7.12、4.58,P http://
  【关键词】 同型半胱氨酸; 游离脂肪酸; 超氧化物歧化酶; 脑梗死
  doi:10.14033/j.cnki.cfmr.2018.1.028 文献标识码 B 文章编号 1674-6805(2018)01-0058-03
  The Study of Homocysteine,Non-esterified Fatty Acid and Superoxide Dismutase in Patients with Cerebral Infarction/XU Gui,YE Meng.//Chinese and Foreign Medical Research,2018,16(1):58-60
  【Abstract】 Objective:To investigate the level of homocysteine(HCY),Non-esterified Fatty Acid (NEFA) and Superoxide Dismutase(SOD) in patients with cerebral infarction.Method:A total of 69 patients with cerebral infarction were selected as research subjects,62 healthy people were compared as normal group.Homocysteine (HCY),Non-esterified Fatty Acid(NEFA),Superoxide Dismutase(SOD) activity were determined by TBA-2000FR automated biochemical analyzer.Result:Compared with the control group,the serum HCY and NEFA levels in the cerebral infarction group were significantly higher,the differences were statistically significant(t=7.12,4.58,P0.05)。     1.2 方法
  1.2.1 标本采集 脑梗死患者入院后,在治疗前,肘静脉采血3 ml,对照组早晨空腹肘静脉采血3 ml。采集的血液在30 min内,3000 γ/min,离心10 min,并在2 h内检测完毕。避免溶血、浑浊和脂血标本。
  1.2.2 测定方法 同型半胱氨酸、游离脂肪酸和超氧化物歧化酶测定试剂盒由北京九强生物技术股份有限公司提供。以上项目均在东芝2000FR全自动生化分析仪上检测。严格按照试剂盒说明书介绍的方法进行操作,室内质控均在控。
  1.3 统计学处理
  采用SPSS 19.0统计软件对数据进行统计分析,计量资料以(x±s)表示,采用t检验;计数资料以率(%)表示,采用字2检验,P参考文献
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  [5]李顺君,吴昊.脑梗死患者血清同型半胱氨酸、叶酸及维生素B12水平的分析[J].国际检验医学杂志,2015,36(7):899-900.     [6]辛续丽,杨桂花,韩静,等.高脂血症人群的血清游离脂肪酸水平调查[J].国际检验医学杂志,2015,36(1):10-11.
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  (收稿日期:2017-06-05)
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