[摘要] 目的 在慢性心肾综合征（CRS）早期诊断中检测N末端B型氨基端利钠肽原（NT-proBNP）和胱抑素C（CysC）及对患者预后效果的评价价值。方法 随机抽取该院2016年5月―2017年5月收治的200例性心力衰竭（CHF）患者展开研究，将其中肾小球滤过率（GFR）低于60 mL/min的100例作为A组；其余GFR超过60 mL/min的100例作为B组，对比两组NT-proBNP、CysC、血清肌酐（Scr）检测结果。结果 ①A组NT-proBNP水平、CysC水平、Scr水平依次是（2.39±0.68）μg/L、（1.75±0.60）mg/L、（388.65±63.23）μmol/L，显著高于B组的（0.82±0.12）μg/L、（0.98±0.34）mg/L、（76.22±10.31）μmol/L，比较差异有统计学意义（P http://
[关键词] 慢性心肾综合；NT-proBNP；CysC；早期诊断；预后评价
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2018）01（c）-0009-03
[Abstract] Objective This paper tries to evaluate the value of N-terminal pro-N-terminal pro-brain natriuretic peptide （NT-proBNP） and cystatin C （CysC） in the early diagnosis of chronic heart-kidney syndrome （CRS） and to evaluate their prognostic value. Methods A total of 200 patients with congestive heart failure （CHF） admitted to this hospital from May 2016 to May 2017 were random selected in this study. 100 patients with glomerular filtration rate （GFR） less than 60 mL/min were selected as group A； The remaining 100 cases of GFR exceeded 60 mL/min as group B， and compared the results of NT-pro BNP， CysC and serum creatinine（Scr）. Results ①The levels of NT-proBNP， CysC and Scr in group A were （2.39±0.68）μg/L，（1.75±0.60）mg/L and（388.65±63.23）μmol/L， significantly higher than that of group B of respectively （0.82±0.12）μg/L， （0.98±0.34）mg/L， （76.22±10.31）μmol/L， with significant difference（P
发表于 2018-8-15 20:50:47