2018冠状动脉支架植入术后阿托伐他汀防治再狭窄的实验临床研究

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　　[摘要] 目的 分析冠状动脉支架植入术后阿托伐他汀应用下对预防再狭窄的效果进行分析。方法 方便选取医院2016年1月―2017年1月收治的行冠脉植架患者86例，采用随机划分方法分为对照组与观察组各43例，观察组冠状动脉支架植入术后给予阿托伐他汀，观察比较两组患者治疗效果、植架情况。 结果 两组患者术前TC、TG、APN等指标差异无统计学意义（P>0.05），术后观察组TC、TG、APN等指标改善明显优于对照组，比较差异有统计学意义（P http://
　　[关键词] 阿托伐他汀；冠脉植架；再狭窄
　　[中图分类号] R541 [文献标识码] A [文章编号] 1674-0742（2018）01（b）-0111-03
　　[Abstract] Objective To analyze the effect of atorvastatin in prevention and treatment of restenosis after the coronary stent implantation. Methods 86 cases of patients with coronary stent implantation admitted and treated in our hospital from January 2016 to January 2017 were selected and randomly divided into two groups with 43 cases in each， the observation group were treated with atorvastatin after the coronary stent implantation， and the treatment effect and stent of the two groups were observed and compared. Results The differences in the TC，TG，APN between the two groups before surgery were not statistically significant（P>0.05）， and the improvement of TC，TG，APN in the observation group after surgery was obviously better than that in the control group， and the difference was obvious by comparison（P0.05），可做比较分析。
　　1.2 方法
　　1.2.1 支架植入术 所有患者均给予冠脉植架治疗，具体流程：①根据患者情况选择合适导引导管，将其沿导引钢丝插入；②保证导引导管位置合理，取导引导丝置入病变血管远端，导引导丝一般以柔软导丝为首选；③于病变位置送预扩张球囊导管，保证球囊充分扩张，使支架顺利植入；④将球囊导管退出，取硝酸甘油注入后观察冠脉痉挛情况，无异常由导引导丝处将支架插入，支架选择可根据患者实际情况而定，植入后需通过造影观察，若支架贴壁良好且无狭窄情况，将球囊导管退出[2]。