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2018原发性肝癌患者介入治疗预后影响因素分析

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发表于 2018-8-14 17:11:30 | 显示全部楼层 |阅读模式
  [摘要] 目的 探讨原发性肝癌患者介入治疗的预后影响因素。方法 方便选取2012年1月―2017年9月该院收治的60例原发性肝癌介入治疗患者为例,依据术后3个月QOL-LC评分分为A组(高于或等于术前,30例)和B组(低于术前,30例),对比观察两组临床资料,Logistic回归分析影响原发性肝癌患者介入治疗预后的影响因素。结果 A组年龄 /6/view-10120409.htm
  [关键词] 原发性肝癌;介入治疗;预后;影响因素
  [中图分类号] R735 [文献标识码] A [文章编号] 1674-0742(2018)01(c)-0099-03
  [Abstract] Objective This paper tries to investigate the prognostic factors of interventional therapy for primary liver cancer. Methods 60 cases of interventional treatment of primary liver cancer patients from January 2012 to September 2017 in this hospital were selected, according to QOL-LC grade of 3 months after operation, they were convenient divided into group A (greater than or equal to the preoperative, 30 cases) and group B (lower than preoperative, 30 cases), the clinical data of two groups were observed and compared, influencing factors of prognosis in patients with primary liver cancer treated by interventional therapy by Logistic regression were analyzed. Results 7 cases of group A, aged less than 40 years old(23.33%), 4 cases of liver function Child grade C (13.33%), 4 cases of TNM stage III (13.33%), Infiltrating type growth mode 6 cases(20.00%), 25 cases of combined medication (83.33%), good mentality of 23 cases(76.67%), with significant difference compared with control group(P    1.3 ?u价标准
  QOL-LC评价标准[3]:量表包括躯体功能、心理功能、症状/副作用、社会功能4个维度,共计评分条目22项,单项评分0~10分。其中6项正向条目,16项逆向条目(计分按“正向”变换),量表评分范围0~220分,评分越高,表示患者生存质量越理想,预后越好。
  病人心态评价标准:以患者精神尚可,依从性佳,能积极配合治疗,乐观向上,无明显焦虑、抑郁、悲观等情绪为心态良好,反之则为不佳[4]。
  1.4 统计方法
  以SPSS 17.0统计学软件进行单因素统计分析,计数资料以[n(%)]表示,结果χ2检验,以Logistic模型对有统计学差异的单因素进行回归分析,P参考文献]
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  [2] 宗迎迎,徐浩,许伟,等.经肝动脉化疗栓塞联合经皮微波消融序贯治疗早期肝癌的疗效及预后影响因素[J].介入放射学杂志,2015,9(3):210-214.
  [3] 倪嘉延,许林锋,陈耀庭,等.联合介入治疗中晚期原发性肝癌远期疗效及影响因素分析[J].中山大学学报:医学科学版,2013,34(5):734-738.
  [4] 谢玉宏.中晚期原发性肝癌介入治疗的疗效及预后[J].实用临床医药杂志,2014,18(3):93-94,97.
  [5] 谭仲俊.原发性肝癌介入治疗后疗效影响因素的分析[J].临床合理用药杂志,2015(26):87-88.
  [6] 王华丽,曹丰,王林,等.多元回归分析在评价中期与晚期肝癌介入治疗预后影响因素中的运用[J].科技资讯,2016,14(36):252-253.
  [7] 银皓,肖琳,詹欣宇,等.肝动脉化疗栓塞治疗乙型肝炎相关性肝癌的预后影响因素[J].临床肝胆病杂志,2014,30(1):50-54.
  [8] 吕嘉玲,杜端明,刘鹏程,等.肝动脉化疗栓塞治疗原发性肝癌的预后因素分析[J].实用放射学杂志,2012,28(1):114-118.(收稿日期:2017-10-28)
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