[摘要] 目的 探究乳腺癌?g后含THP（吡柔比星）辅助化疗临床价值。方法 方便选取该院肿瘤科化疗一区2016年3月―2017年3月收治的74例乳腺癌患者，均于乳腺癌术后进行辅助化疗，依据辅助化疗方案不同分成对照组（37例）与研究组（37例），对照组实行以ADM（多柔比星）为主的辅助化疗方案，研究组行以THP为主的辅助化疗方案，比较两组临床疗效、毒副反应、骨髓抑制程度。结果 研究组与对照组化疗有效率分别为94.59%、91.89%，两组差异无统计学意义（P>0.05）；研究组心脏毒性与脱发总发生率分别为16.21%、40.54%，均较对照组低（P0.05），化疗后研究组血白细胞含量（3 590.45±136.95）×106/L高于对照组，差异有统计学意义（P /6/view-10741990.htm
[关键词] 乳腺癌；术后；辅助化疗；THP
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2017）08（c）-0131-03
Clinical Research on ADM Containing THP after the Breast Cancer Surgery LAN Bi-quan， FENG Guo-sheng
One Chemotherapy Area， Department of Oncology， Guangxi Zhuang Autonomous Region People's Hospital， Nanning， Guangxi， 530021 China
[Abstract] Objective To study the clinical value of adjuvant chemotherapy？containing THP after the breast cancer surgery. Methods 74 cases of breast cancer patients admitted and treated in our hospital from March 2016 to March 2017 were convenient selected and underwent the adjuvant chemotherapy after the breast cancer surgery， and the patients were divided into two groups according to the different adjuvant chemotherapy plans with 37 cases in each， the control group adopted the adjuvant chemotherapy plan with ADM as the main， while the research group adopted the ADM with THP as the main， and the clinical curative effect， toxic and side effect and bone marrow suppression degree were compared between the two groups. Results The chemotherapy effective rate in the research group and in the control group was respectively 94.59% and 91.89%， and there was no obvious difference between the two groups（P>0.05）， and the total incidence rate of cardiotoxicity and alopecia in the research group was respectively 16.21% and 40.54%， which were lower than those in the control group（P0.05）， after chemotherapy， the white blood cell content in the research group was （3 590.45±136.95）×106/L， which was higher than that in the control group， and the difference was statistically significant（P
发表于 2018-8-15 10:57:58