1855121 发表于 2018-8-17 16:34:39

2018糖尿病性脑血管病变患者脑血流指标及微循环状态的变化观察

  [摘要] 目的 观察与探究糖尿病性脑血管病变患者脑血流指标及微循环状态的变化情况。方法 选取2013年10月―2015年7月期间该院收治的75例糖尿病性脑血管病变患者为A组,75例糖尿病无脑血管病变患者为B组,75名健康同龄者为C组,然后检测及比较3组的脑血流指标及微循环状态相关指标,并比较A组中大血管病变与微血管病变患者的脑血流指标及微循环状态相关指标。结果 A组的脑血流指标及微循环状态相关指标均差于B组及C组,B组则差于C组,A组中大血管病变患者的检测结果差于微血管病变患者,差异有统计学意义(P http://
  [关键词] 糖尿病性脑血管病变;脑血流指标;微循环状态
  [中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2017)06(a)-0174-04
   Objective This paper tries to observe and investigate the change of cerebral blood flow indexes and microcirculation state of patients with diabetic cerebrovascular disease. Methods 75 patients with diabetic cerebrovascular disease in this hospital from October 2013 to July 2015 were selected as group A, 75 patients with diabetes mellitus and without cerebrovascular disease were selected as the group B, 75 healthy persons of the same age were selected as group C, then the cerebral blood flow indexes and related microcirculation state indexes of three groups were detected and compared, then the cerebral blood flow indexes and related microcirculation state indexes of group A with large vessel lesion were compared too. Results The cerebral blood flow indexes and microcirculation state related indexes of group A were worse than those of group B and group C, the results of group B were all worse than those of group C, and the detection results of group A with large vessel lesion were all worse than those of patients with microvascular disease, the differences were all significant(P0.05),A组与B组的糖尿病病程及分型构成差异无统计学意义(P>0.05),见表1。
  1.2 方法
  分别检测3组研究对象的脑血流指标及微循环状态相关指标,脑血流指标采用脑血管血液动力学监测仪进行检测,检测指标为Vmean、Vmin、Zcv、RV、DR及CP,另进行3组的微循环状态相关指标的检测,其包括甲襞微循环(加权总积分、白微栓率、管襻畸形率、襻顶直径及管襻长度)与血液黏度指标(血浆黏度、全血高切及低切黏度、全血还原高切及低切黏度),其分别采用微循环检测仪及全自动血液流变分析仪进行检测。然后统计及比较3组的脑血流指标及微循环状态相关指标,并比较A组中大血管病变与微血管病变患者的脑血流指标及微循环状态相关指标。     1.3 统计方法
  数据检验方面采用SPSS 6.0统计学软件进行分析,计量资料采用(x±s)表示,进行t检验,计数资料用表示,进行χ2检验,P参考文献]
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  (收稿日期:2017-03-09)
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