2018胰岛素治疗妊娠期糖尿病的疗效及母婴风险
[摘要] 目的 胰岛素治疗妊娠期糖尿病的疗效及母婴风险分析。 方法 将该院就诊的60例妊娠糖尿病患者按照随机数字表法分为两组,分别采用单纯饮食控制(对照组30例)与胰岛素治疗(观察组30例),比较两组血糖水平的变化情况及母婴不良结局发生情况。结果 观察组患者空腹血糖及餐后2 h血糖、糖化血红蛋白均明显优于对照组(P http://[关键词] 胰岛素;妊娠糖尿病;母婴不良结局
[中图分类号] R714 [文献标识码] A [文章编号] 1672-4062(2017)06(a)-0087-02
Objective This paper tries to analyze the curative effect and maternal risk of insulin treatment of gestational diabetes. Methods 60 cases of gestational diabetes in this hospital were randomly divided into two groups by random number table method, 30 cases in the control group were treated by diet control only and 30 cases in the observation group were treated with the insulin treatment, the incidence of blood glucose levels between the two groups and the changes of maternal adverse outcomes were compared. Results Fasting blood glucose and 2 hours postprandial blood glucose, HbA1c in the observation group were significantly better than the control group (P统计学意义(P>0.05),可对比。
1.2 治疗方法
对照组仅采用常规饮食干预进行血糖控制,即在妊娠期间给予患者必要的营养及供给,并合理调整脂肪、糖类、蛋白质等物质的比例。且需严格控制钠盐的摄入量,通常摄入量应小于6 g/d。观察组则在对照组饮食干预的同时配合胰岛素治疗,注射用药,用药量根据患者孕周情况进行调整;对于孕周低于30周者,每天注射量为0.8 U/kg;孕周为30~35周者,注射量为0.9 U/kg,1次/d。孕周≥35周者,注射量为1.0 U/kg,1次/d。之后根据患者血糖水平对用药剂量进行合理的调整。
1.3 观察指标
①对比两组血糖水平变化情况,包括空腹血糖、餐后2 h血糖、糖化血红蛋白水平;②对比两组母婴不良结局。
1.4 统计方法
用以SPSS 18.0统计学软件处理数据资料,计量资料表现形式为(x±s),开展t检验,计数资料开展χ2检验,P
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