2018癫痫患儿早期治疗对预后评估的分析
[摘要] 目的 分析癫痫患儿早期治疗临床恢复情况以及预后评估情况。方法 随机选取该院2014―2016年确诊收治的30例癫痫患儿给予早期治疗(即为实验组)。选择同期确诊6个月后开始进行治疗的30癫痫患儿(即为对照组),两组患儿治疗后比较两组患儿预后效果并评估两组患儿预后发育情况。结果 实验组患者临床治疗有效率明显优于对照组(96.7% vs 86.8%),实验组患儿治疗后Engel分级明显优于对照组患儿,实验组EngelIII级2例,对照组EngelIII级4例,差异有统计学意义(P http://[关键词] 癫病患儿;早期治疗;预后评估
[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2017)10(c)-0063-03
Prognostic Evaluation of Early Treatment for Children with Epilepsy
LU Hong-li
Wenshan Maternal and Child Health Care Family Planning Service Center, Wenshan, Yunnan Province, 663099 China
Objective This paper tries to study the clinical recovery and prognosis analysis of early treatment of children with epilepsy. Methods 30 cases of children with epilepsy were randomly selected in this hospital from 2014 to 2016 with early treatment (regarded as the experimental group). 30 epileptic children diagnosed during the same period after half a year (regarded as the control group), the prognosis and the body development of the two groups were compared and evaluated. Results The clinical effective rate of the experimental group was significantly better than the control group(96.7% vs 86.8%), in the experimental group after treatment, Engel classification was significantly better than the control group, 2 cases in experimental groug of EngelIII, 4 cases of grade EngelIII in the control group, the difference was statistically significant (P0.05),可进行对比分析。
1.2 病例选择标准
该院2014―2016年收治的60例患儿均符合小儿癫痫的临床诊断标准。 ①症状:患儿早期出现焦虑不安、惊恐压抑等情绪上的改变,部分患儿甚至出现幻觉,肢体麻木刺痛、局部肌肉以及肌群出现不自主的颤抖,患儿发作时出现意识障碍,发作结束后可恢复正常,发作次数以及发作平率不断增加,部分患儿出现嗅觉、味觉异常改变。②影像学检查:患儿发作时脑电波出现异常波动,脑电图显示患儿发作时出现异常改善,进行CT、磁共振检查能及时发现患儿脑部致痫性损伤。所有患儿均签署相关知情协议,并表示能配合复查随访工作。
1.3 方法
实验组30例患儿确诊后给予早期治疗,对照组同期确诊,癫痫持续发作3个月后给予治疗,所有患儿入院后均完善相关检查并确诊,实验组与对照组患儿均给予丙戊酸钠(国药准字:H43020874)、卡马西平(国药准字:H44023982)、苯巴比妥(国药准字:H14023928)等常规药物治疗,丙戊酸钠3次/d,口服20 mg/(kg?g),1周后给药剂量增加5 mg/kg、卡马西平对于6岁以下患儿,口服1次/d,?o药量按照5 mg/(kg?g),1周后给药剂量增加至10 mg/kg,苯巴比妥3次/d,口服3 mg/(kg?g)。对于药物治疗无效,且存在脑内致痫性损伤的患儿,根据脑损伤情况制定相应的手术治疗以及围手术期护理。
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