9099715 发表于 2018-8-16 21:37:08

2018硝酸甘油与垂体后叶素治疗支气管扩张伴咯血的临床疗效分析

  [摘要] 目的 分析硝酸甘油与垂体后叶素治疗支气管扩张伴咯血的临床效果。方法 方便选取来该院就医的支气管扩张伴咯血患者60例、(2015年1月―2017年1月)作为该次研究的对象,通过动态化随机单双号分组的方法将其分为2组,每组30例,分别给予硝酸甘油、垂体后叶素联合硝酸甘油治疗,对比2组患者治疗效果、咯血时间、总咯血量、不良反应发生情况的差异性。结果 观察组患者的治疗总有效例数为28例、咯血时间为(7.20±1.11)d、总咯血量为(521.54±128.69)mL、不良反应发生例数为4例,其结果与对照组患者的结果相对比,差异有统计学意义(P http://
  [关键词] 硝酸甘油;垂体后叶素;支气管扩张;咯血;临床疗效
  [中图分类号] R562 [文献标识码] A [文章编号] 1674-0742(2017)10(c)-0142-03
  Clinical Analysis of Nitroglycerin and Pituitrin in the Treatment of Bronchiectasis with Hemoptysis
  LYU Jian, TANG Liang-fa, LIU Cheng-ying
  Department of Respiratory Medicine, Jiangyin People’s Hospital, Jiangyin, Jiangsu Province, 214400 China
   Objective This paper tries to analyze the clinical effect of nitroglycerin and pituitrin on bronchodilator with hemoptysis. Methods 60 patients with bronchiectasis and hemoptysis from January 22nd, 2015 to January 23rd, 2017 were selected as the subjects of this study, and were divided into two groups by dynamic randomized single-double grouping method, with 30 cases in each group, and was respectively given nitroglycerin, pituitrin combined with nitroglycerin treatment, and then the treatment effect, hemoptysis time, total hemoptysis, adverse reactions of the two groups were compared. Results The total effective number of patients in the observation group was 28, the hemoptysis time was(7.20±1.11)d, the total hemoptysis was(521.54±128.69)mL and the number of adverse reaction cases was 4, which was significantly different from those in the control group(P0.05),可对比。     1.2 方法
  对照组采用垂体后叶素治疗:在第1次治疗的时候,将10U垂体后叶素(国药准字 H12020786)与20 mL生理盐水进行融合,之后对患者实施推注治疗,在治疗的时候,还需要采用18U垂体后叶素与500 mL生理盐水融合进行静脉滴注。观察组采用硝酸甘油联合垂体后叶素治疗:将10 mg硝酸甘油(国药准字H20058649)与250 mL生理盐水进行融合,之后进行静脉滴注治疗,垂体后叶素治疗方法与对照组相同。2组患者均治疗1周。
  1.3 观察指标
  观察2组患者治疗效果、咯血时间、总咯血量、不良反应发生情况的差异性。治疗效果:分为显效、有效、无效3个指标,其中,显效表示在治疗后,患者的临床症状已经消失,且患者的咯血情况在48 h内停止;有效表示在治疗后,患者的临床症状逐渐消失,且患者在48 h之内依旧存在较少的咯血情况;无效表示在治疗后,患者的临床症状与治疗前相同,且咯血症状依旧存在。不良反应发生情况:心悸、头晕、腹泻、高血压等。
  1.4 统计方法
  采用SPSS 21.0统计学软件进行数据统计,其中计量资料、计数资料表示为(x±s)和的形式,分别进行t检验、χ2检验。P参考文献]
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  (收稿日期:2017-07-28)
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